ANTIBIOOTTIEN HAITALLISUUDESTA

[Bb]

Lähettäjä: Soijuv Lähetetty: 12.2.2006 12:50

Antibiootteja tarvitaan infektiotautien torjuntaan, mutta niiden haitoista on syytä olla selvillä. Suurin osa elimistön bakteereista on haitattomia tai hyödyllisiä, esim. suoliston mikrobisto. Antibiootit eivät kuitenkaan erottele elimistön hyvien ja huonojen bakteerien välillä, vaan tuhoavat erottelematta kumpiakin. Ne tappavat mm. sellaiset suolistobakteerit jotka valmistavat B12-vitamiinia.

Antibioottien mahdollisia muita haittoja ovat esim:

munuais./maksavaurio, heikentävät immuunijärjestelmää, aikaansaavat hiivan liikakasvua, liiallinen käyttö voi aikaansaada ns. "superinfektion", Esim. penisilliinin on todettu aiheuttavan mm. erilaisia ihoreaktioita (exfoliative dermatitis, maculopapular eruptions, necrotizing dermatitis, purpura (hemorrhagic disease); munuaisvaurioita (angiitis renal artery inflammation), glomerulonephritis, acute nephritis, eosinofiilistä keuhkokuumetta, valoherkkyyttä, kuumetta, verenvuotoa, hermovaurioita ja lihaskipuja. Myös SLE-taudin puhkeaminen on todettu joidenkin antibioottien käytön kohdalla.

Huom. Borrelioosi aiheuttaa ilman antibioottien käyttöäkin toisinaan esim. munuais-/munuaiskerästulehdusta.


Antibiotics in our bodies cannot tell the cops from the robbers. With no discretion, they kill friendly as well as harmful bacteria. It is usually not recognized that for every injurious or parasitic microbe, there are dozens of beneficial ones. The majority of bacteria are helpful, actually working for us, and are a source of nutrition, like the microflora in our intestines. Antibiotics kill the friendly bacteria that manufacture vitamin B12 in the gut. Where's the logic in depressing our immune system to fight an infection artificially? Humans and other animals don't produce antibiotics, nor do they need to, if their endocrine, immune, and nervous systems have the mineral, vitamin, protein, and enzyme substances found in foods grown on mineral-rich soil. Armed with these tools, the Earth's highest forms of life--humans and animals are well equipped to fight the Earth's lowest forms of life--bacteria and fungi. This has kept human beings surviving for at least 100,000 generations. Nature's track record for being right should inspire our trust. Dr. Richard Novick, Public Health Research Institute, New York City, on the subject of antibiotics, says, "Doctors use them as a crutch for an easy way to take care of patients, and drug companies have a financial stake in selling them as fast as they can."

Today, about 15 million pounds a year, nearly half of U.S. production of antibiotics, is fed to farm animals, primarily cattle, poultry and pigs--$270.9 million worth in 1983. It has been shown how antibiotic-resistant bacterium, in addition to residual antibiotics, can make their way from the barnyard to the dinner table and into the humans who eat it. Antibiotics have not made any significant changes in the plague of human diseases. Pathologist Widmann of Duke University stated: "Wonder drugs have not eradicated infectious disease; they have merely changed the conditions and natural history of many infections. They have, however, contributed to immunosuppression, perhaps setting the stage for AIDS. Antibiotics, instead of assisting the inflammatory repair process, inhibit both chemotaxis and phagocytosis, which are essential to the healing of damaged tissue. Antibiotics have been implicated in causing as many as 300,000 disease reactions per year with up to 90,000 deaths per year resulting therefrom. Antibiotics have caused immunologic reactions such as: (a). anaphylaxis, (b.) urticaria, (c.) Coomb's-positive hemolytic anemia, (d.) serum sickness and (e.) morbilliform eruptions, resembling measles."

Antibiotics cause gastrointestinal reactions by direct irritation of the mucous membrane, destruction of normal, natural bacterial flora or by creating bacterial overgrowth of abnormal forms. Antibiotics eliminate organisms from the normal flora of the skin, oral and genito-urinary mucosa and promote growth of drug-resistant organisms. Oral or vaginal candidiasis (thrush) often follows the use of broad-spectrum antibiotics. Now, if the Ehrlich/Metchnikoff germ theory was still a contender in the ring of disease causation, which it's not, the antibiotic approach to disease treatment might have some credibility. It is worth noting that the term antibiotic is from root words that mean "against life" and is defined by the medical dictionaries as: (1) destructive of life, (2) a chemical substance produced by a microorganism, which are able to kill other microorganisms.

The layman's dictionary simply tells us that antibiotics are substances having the power to arrest or kill microorganisms called germs. The incidence of infections in wounds caused by injury or operations has not decreased despite the use of antibiotics for more than twenty-five years, declared bacteriologist and surgeon Dr. William Altemeier to a meeting of the American College of Surgeons. His study revealed that antibiotics may actually have increased the number and complexity of problems related to infections. In 1972, the U.S. Senate Small Business Monopoly Subcommittee held hearings about drug abuse, and Dr. Henry E. Simmons made known some very important facts about antibiotics. At that time, Dr. Simmons was director of the Bureau of Drugs in the FDA and blamed doctors who prescribed antibiotics routinely for creating additional problems. Simmons explained that "the inappropriate use of an antibiotic can result in the appearance of resistant strains of bacteria with an increased number of superinfections." He explained to the subcommittee that one of the major problems in medicine today was the sharp rise in hospital-treatment-caused superinfections he called blood poisoning. Simmons and other doctor-witnesses testified to the facts that: (1) "Antibiotics possibly cause 100,000 to 300,000 iatrogenic cases each year of which 30% to 50% are fatal." (2) "60% of hospital patients who receive antibiotics don't need them." (3) "Production of antibiotics has increased 300 percent in 10 years--in 1972 reaching 2.4 million kilograms."

This would mean, that in 1972, enough antibiotics were produced to give every man, woman and child in the U.S. 50 doses, a drop in the bucket compared to production in 1982. (4) In a letter by FDA to national medical groups, pertinent excerpts pointed out that: (a) Antibiotics are being massively introduced when not indicated and are often misused. (b) Indiscriminate or inappropriate use of antibiotics is detrimental. Robbins and Cotran's Pathologic Basis Of Disease, 1979, tells us that over 90% of hospital isolates of staphylococci from patients with serious infectious diseases are penicillin-resistant and that gonococci have become resistant to the tetracyclines, streptomycin and sulfonamides. "Drug resistance has been documented for many microbes, and so it has become a race between the ingenuity of man in developing new drugs and the ingenuity of the microbes in achieving methods of survival." Or, could it be that an intelligent Creator designed the microbe to adapt to chemical insult, in order to continue its scavenger function of dissolving dead cells so that man can keep living in spite of his evolutionary ignorance? In 1972, Harry Dowling, a former chairman of the Council on Drugs of the AMA, testified before the Senate Monopoly Subcommittee and cited FDA data that doctors prescribe 10 to 20 times as many antibiotics as are medically justified. Dowling said, "It is doubtful that the average person has an illness that requires treatment with an antibiotic more often than once every five or ten years."

The late Dr. Robert Mendelsohn, M.D., in his book, Confessions of a Medical Heretic, had a few remarks about antibiotic misuse and told us: (1) "...these 'miracle' drugs that were once extremely valuable are now extremely dangerous. (2) "Penicillin and other antibiotics do not shorten the course of the disease, do not prevent complications, and do not reduce the number of pathogenic organisms in the nose and throat. They do no good at all. (3) "...Chloromycetin (chloramphenicol) has the common, fatal side effect of interfering with the bone marrow's production of blood." About Chloromycetin, Mendelsohn says that if a person's life is at stake, using this drug could be an acceptable risk to take. But if a child suffers nothing more than a sore throat, "is the non-relief chloromycetin might bring worth risking depression of the child's bone marrow, requiring multiple transfusions and other therapies, none of which will guarantee complete recovery?" (4) Tetracycline became so popular it became known as the 'house call' antibiotic. He relates that the FDA finally required a warning on all packages informing that in late pregnancy, infancy, and to the age of 8--it can cause permanent yellow-gray-brown discoloration of teeth including malformed tooth enamel. Mendelsohn, who was an Associate Professor of Medicine, warns that 8 to 10 million Americans go to the doctor, each year, for a cold. Ninety-five percent get a prescription and at least 50% are for antibiotics, which are not even indicated for a cold. He says, "Not only are these people duped into paying for something which has no effectiveness against their problem, but they are set up for the hazards of side effects and the risks of deadlier infections."

Daniel L. Azarnoff, M.D., University of Kansas Medical Center, writing in the book Controversies in Therapeutics, 1980, comments, "A study of 50 randomly selected charts from one week in June 1973, at a well known medical center showed that 56 courses of antibiotics were given. Of all the prescriptions for antibiotics, 63% were considered not indicated, inappropriately selected or given in wrong doses." Dr. Azarnoff, in his study entitled Monitoring and Control of Physician Prescribing Are Needed tells us a few things that are hard to believe: The average doctor writes approximately 8,000 prescriptions per year. In one study involving 1,608 patients receiving antibiotics, 62% had no evidence of infection, which would not indicate a need for antibiotics. Of 254 patients receiving the drug spironalactone in a university hospital, 104 were also receiving potassium chloride, which in combination, frequently has deleterious effects on humans. He warns: "If misuse of drugs occurs at teaching institutions that have strong peer review and supervision, what's happening in less-well-supervised situations? In one recent year, nearly 7 million ounces of antibiotic Tetracycline syrup was prescribed. Ninety-nine percent went to children under 8 years of age. This particular drug produces symptoms similar to brain tumors and can cause mouth and kidney infections, rectal disease, kidney failure, permanent tooth damage and inhibition of bone growth." This information comes from Dr. Summer Yaffe, chairman of the Committee of Drugs for the American Academy of Pediatrics in Philadelphia. Dr. Yaffee warns, "You don't need tetracycline. It's not effective, and it's toxic. In small children, it can cause the skull to bulge." The condition mimics a brain tumor so closely that in some cases babies had to undergo surgery. The anguish and expense parents go through makes it clear that more stringent controls should be put on this drug.

Friendly Bacteria

Antibiotics (prescription or residues in meat & poultry) cause improper or insufficient bacteria in the bowel. The ability of intestinal flora to metabolize nutrients, hormones, bile acids, cholesterol and carcinogens is well established. Over 400 species of microorganism inhabit the healthy human gut and contribute four pounds to overall body weight. The ecology of these microorganisms is very important to the health of the human body. The balance of this ecology can significantly affect lactose tolerance, serum cholesterol levels, tumor growth or suppression, serum steroid hormone levels, immune function, the proliferation of pathogenic organisms in the gut, bowel transit time and other aspects of metabolism. Relatively few bacteria, between 10 and 100 organisms per ml. of stomach contents, are commonly found in the healthy human stomach. Concentrations of one trillion organisms per ml. of content are common in the colon.

Immune Suppression

Scientific American Medicine, 12/80, 7:-1, states, "In the past decade, there have been major advances in the use of immunosuppressive drugs in organ transplantation. An important side effect, however, has been the creation of a group of patients with major defects in host defense against infection. Therapeutic programs that may have an adverse effect on a patient's ability to withstand infection include antibiotics, radiation therapy, corticosteroids (cortisone-prednisone), and cytotoxic agents. Thus, antibiotic therapy should be as specific as possible and should not be used needlessly." One type of adverse reaction from antibiotics is called cytotoxic and an antibody theoretically mediates it. By whatever mechanism, the drug serves as a haptene and results in an immugenic action. Some of the adverse consequences of the "cytotoxic response" include hemolytic anemia, agranulocytosis and thrombocytopenia associated, supposedly, with the autoimmune mechanism. This ignores the true cause--drugs--and sets up a make-believe situation that blames the consequent pathology on patients' natural ability to cope with any physiological insult, as well as the drug insult.

Penicillin and streptomycin are more often associated with hemolytic anemia; a break down of the red blood cell wall, while streptomycin, chloramphenicol, antihistamines and sulfonamides, like HEAVY METALS, interfere with the body's ability to produce neutrophils, which is called neutropenia. The periodical Current Therapy, 1983 revealed a few side effects from Penicillin. They are:

1. Skin reactions--a. exfoliative dermatitis; b. maculopapular eruptions; c. necrotizing dermatitis; d. purpura (hemorrhagic disease).

2. Kidney reactions--a. angiitis (renal artery inflammation); b. glomerulonephritis; c. acute nephritis.

3. Other reactions and symptoms--a. eosinophilic pneumonia; b. photoallergic sensitivity; c. drug fever; d. symptoms such as dyspnea, fever, bleeding, nerve damage and painful muscles.

4. Systemic Lupus Erythematosus has been induced by Procainamide, Isoniazid, Quinidine, and Griseofulvin, as well as by Penicillin.

Not only are antibiotics not needed nor even indicated, they are classified as immunosupressive drugs, which impair the human immune system. How many fatal cases of AIDS are, in truth, the after-effect of irrationally prescribed antibiotics? Many antibiotics have a nephro (kidney) toxicity factor of 20% and several antibiotics have hepa (liver) toxicity factor more than 20%. Since most antibiotics inhibit chemotaxis and phagocytosis, they definitely impair the immune system, and, in turn, can and will contribute to AIDS. In the journal, Diseases of the Chest, (39, 630-642: 1961), two chest specialists, Sidransky and Pearl, blatantly cautioned, "Invasive pulmonary aspergillosis almost always follows antibiotic or steroid (cortisone/prednisone) therapy and is increasing in incidence." In other words, the administration of antibiotics or steroids destroys the normal, needed bacteria in the respiratory tract, which digest and destroy yeast cells. Devoid of proper bacterial flora, the stage is set for the invasion of yeast organisms such as aspergillosis and histoplasmosis spores. Both conditions can lead to pneumonia and influenza-type illness. Fatal Aplastic Anemia after Chloromycetin and Tagamet has been reported in the Physicians Drug Alert--April 1982. On day 32, the marrow was aplastic, on day 34, the patient died. Both Chloromycetin and Tagamet can cause bone-marrow suppression.

Chloromycetin causes reversible and irreversible pancytopenia. Most cases of Chlormycetin-induced aplastic anemia occur 2 weeks to 12 months after oral administration. Three cases of Tagamet-associated pancytopenia have been reported with marked marrow hypoplasia in one patient. How many unreported cases? Pancytopenia (PCP) exists when platelets, white cells and red cells are all diminished; an indication of bone marrow depression. When due to drugs, it is also called secondary aplastic (hypoplastic) anemia. Most cases of leukopenia, which means a white blood cell count under 4,800, are usually due to a decrease in neutrophils-called polys or polymorphonuclear leukocytes. Neutrophils, as already mentioned, constitute the body's first line of defense when tissues are damaged. By chemotaxis, neutrophils promptly migrate to areas of inflammation and phagocytize (engulf) foreign matter and other necrotic debris. Dr. W. Eugene Sanders, associate Professor of Medicine and Microbiology, University of Florida College of Medicine, was quoted in the Health Bulletin, Vol.9 No.3, that, "there was a time when there was so much penicillin used on hospital wards that one could detect minute organisms of penicillin in the air." He cautioned that doctors prescribe antibiotics too frequently, in too high doses or when they are not needed and this is upsetting the ecology of the human body and making it more difficult for the natural defense system to do its job. He goes on to state, "This is not just a problem confined to physicians...It is prevalent in the best teaching institutions of this country." Killing the myth is much more difficult than killing bacteria. The mystery of the effectiveness of antibiotics is decided in the petri dish or culture plate. Antibiotics in vitro (test tube or petri dish) kill microorganisms by weakening the cell walls.

But...in the body--in vivo--the real effect is the enzymatic blockade of reactions of cellular biochemistry needed for repair or replacement. A problem in this area was made manifest by F.K. Widmann, M.D., assistant Professor of Pathology at Duke University School of Medicine. Dr. Widmann stated that culture contamination is by no means uncommon and that detergents, alcohol sponges or other skin cleaners are not adequate when doing venipunctures to obtain blood for culturing. With millions of bacteria inhabiting a single breath of air and thousands of bacteria being pushed under the skin and into the bloodstream with each hypodermic needle insertion--it becomes evident that sterility of specimen and non-contamination of Petri cultures is a sheer impossibility. Gram-positive or gram-negative bodies resembling yeasts may be seen in spinal fluids shortly after myelograms...obviously an artifact introduced into the spinal fluid by the hypodermic needle. In the case of tetracyclines, they enter the mitochondrion (power plant of the cell) and induce defective oxidative phosphorylation, which brings inflammatory repair to a halt. Steroids such as Cortisone and Prednisone are pharmacologically designated as anti-inflammation agents and do just that...stop inflammation.

All authorities on chemotherapy of microbial diseases relate that in the selection of antimicrobial drugs and treatment guidelines, identification of the causative organism is essential to the appropriate antimicrobial drug selection and successful treatment of infections. If microorganisms cause disease, it would, naturally, be of scientific benefit to identify the culprit and then administer an effective chemotherapeutic agent with selective toxicity. Selective toxicity means the ability to kill (bactericidal) or inhibit (bacteriostatic) microorganisms without harming or killing the host (patient). Bactericidal type chemotherapeutic agents called antimicrobials include: 1. Penicillins; 2. Cephalosporins; 3. Aminoglycosides such as Streptomycin, Neomycin, Kanamycin, Gentamycin, Tobramycin and Amikacin; 4. Vancomycin; 5. Polymixin, Polymixin B and Colistin.

Bacteriostatic agents include the following: 1. Sulphonamides (SO2NH2), sulfa-like compounds; 2. Trimethoprim; 3. Tetracyclines; 4. Chloramphenicol; 5. Erythromycin; 6. Lincomycin or Clindamycin. This specificity factor has been determined in a petri dish by disk diffusion. The problem, or example, is seen in the fact that almost 100% of salmonella bacteria are susceptible, in vitro, to Gentamycin or Colistin, but in vivo (in the body) are diagnosed as systemic salmonellosis, there's no therapeutic benefit derived from this antibiotic. Also, subacute bacterial endocarditis is supposedly caused by the bacteria viridans streptococci. In the dish, chloramphenicol destroys the microorganism almost 100% whereas in the blood, the antibiotic has no clinical benefit at all.

If you stop the first phase of the biochemistry of inflammation by administering an antihistamine, which neutralizes the histamine and relieves brawny induration or swelling...relief of symptoms occurs, but there is no repair. If you give an antipyretic and stop the hyperemia with its accompanying heat or fever, you have symptomatic relief, but there is no repair. You can administer an antibiotic or steroid hormone with abatement of symptoms, but there is no repair.'....

Koko Artikkeli: http://tuberose.com/Antibiotics.html