MIKROBIT PSYYKKISTEN SAIRAUKSIEN TAUSTALLA

[Bb]

Lähettäjä: Soijuv Lähetetty: 28.4.2006 10:40

"Useat mikrobeihin liittyvät tekijät näyttävät olevan psyykkisten sairauksien taustalla. Skitsofrenia ja useat muut psyykkiset sairaudet vaativat saksalaisen tutkimuksen mukaan pitkäaikaista immunoterapiaa.Tutkimuksessa immunoterapiasta saatiin hyviä tuloksia skitsofreniaa, bipolaarista häiriötä ja autismia sairastavilla henkilöillä."


Med Hypotheses. 2002 Aug;59(2):154-8.
Schizophrenia and other mental disorders require long-term adoptive immunotherapy.

Wank R.

Institute of Immunology, Klinikum Innenstadt, University of Munich, Goethestrasse 31, 80336 Munich, Germany. wank@ifi.med.uni- muenchen.de

Many different microbial factors seem to contribute to the pathogenesis of schizophrenic and other psychiatric disorders. Activation of all T lymphocytes reactivates those downregulated by low-grade chronic infections and restores equilibrium in immune cell subpopulations.

Different immune cell subpopulations express different neurotrophin receptors and produce different cytokines, particularly brain-derived neurotrophin (BDNF) and neurotrophin 3 (NT3) [M. Besser, R. Wank, J. Immunol. 162 (1998) 6303-6306] that appear to play a key role in schizophrenic and bipolar disorders [E. Jonsson, S. Brene, X.R. Zhang, et al., Acta Psychiatr. Scand. 95 (1997) 414-419; R.S. Duman, Arch. Gen. Psychiatry 54 (1997) 597-606; J.A. Siuciak, D.R. Lewis, S.J. Wiegand, R.M. Lindsay, Pharmacol. Biochem. Be 56 (1997) 131-137]. The hypothesis that adoptive immunotherapy is effective in psychiatric disorders will be supported by three case reports, in a patient with bipolar disorder, a patient with schizophrenia, and a patient with autism.

PMID: 12208201 [PubMed - indexed for MEDLINE]