METELIN SIETO ALHAINEN

[Bb]

Lähettäjä: Soijuv Lähetetty: 18.1.2006 14:04

Audiologic Manifestations of Patients with Post-Treatment Lyme Disease
Syndrome.
Ear & Hearing. 24(6):508-517, December 2003.
Shotland, Lawrence I.; Mastrioanni, Mary Ann; Choo, Daniel L.;
Szymko-Bennett, Yvonne M.; Dally, Leonard G.; Pikus, Anita T.; Sledjeski,
Kathryn; Marques, Adriana

Abstract:
Objective: The purpose of this study was to characterize auditory function
in patients diagnosed with post-treatment Lyme disease syndrome (PTLDS).

Design: Eighteen patients with PTLDS were evaluated and compared to a normal
population. Evaluations consisted of pure tone and speech thresholds, word
recognition (WRS), acoustic immittance battery, auditory brain stem response
(ABR), and loudness discomfort level (LDL). Both seropositive and
seronegative patients were evaluated. Audiologists were blinded to patient
status.

Results: Forty four percent of the patients had one or more abnormal pure
tone thresholds compared to gender- and age-adjusted norms. Thirty-one
percent showed abnormally reduced LDLs, and 17% had abnormal acoustic
reflexes at one or more frequencies.

Conclusions: This paper catalogs previously unstudied long-term auditory
system sequelae resulting from PTLDS. Our most significant finding was the
dramatically reduced loudness tolerance in the presence of either normal or
minimally impaired hearing. The clinician is encouraged to consider PTLDS
when confronted with these or similar findings in patients having history of
Borrelia burgdorferi infection and continued complaints.

Tutkimuksen mukaan kroonista borrelioosia sairastavilla
on selkeästi alentunut metelin sietokyky. Tutkimuksessa
kroonisesta borrelioosista käytettiin nimeä "Hoidon jälkeinen
Borrelioosi" (Post treatment LD).