Lähettäjä: Soijuv Lähetetty: 18.10.2005 15:21
Tässä vuoden 1992 tutkimuksessa ei löydetty todisteita sille että Bb leviäisi verenluovutuksen kautta:
Infusionsther Transfusionsmed.
1992 Aug;19(4):204-7. Related Articles, Links
Screening of blood donors and recipients for Borrelia burgdorferi antibodies: no evidence of B. burgdorferi infection transmitted by transfusion.
Bohme M, Schwenecke S, Fuchs E, Wiebecke D, Karch H.
Abteilung fur Transfusionsmedizin und Immunhamatologie, Universitatsklinikum, Wurzburg, FRG.
In the study presented here, the prevalence of antibodies against Borrelia burgdorferi, the etiologic agent of Lyme borreliosis, was determined in a group of blood donors from the Wurzburg area (Southern Germany). 13 of 472 donors (2.7%) tested were positive by immunoblotting (IB). These 13 donors were examined in more detail by physical examination, anamnesis and determination of inflammation parameters of the blood. All persons were asymptomatic for Lyme borreliosis. One of 5 who remembered a tick bite actually had suffered from an erythema chronicum migrans 5 years ago. Another one had been affected by fever, headaches and pain in the limbs, arthralgia and motoric disorder in both hands 6 months before examination. Analysis of the blood did not provide any evidence of an acute infection. Moreover, each of the 472 serum samples was analyzed by a hemagglutination test (HAT). 26 (5.5%) showed a positive test result. In order to investigate whether a seroconversion of the recipients by transfusion of B. burgdorferi antibody-positive blood had taken place, 9 recipients of blood products originating from the 13 IB-positive donors were serologically reexamined. All samples taken proved to be antibody-negative. Consequently, the transfusion did not produce any seroconversion in the patients thus treated.
PMID: 1422081 [PubMed - indexed for MEDLINE]
BB/VERENLUOVUTUS
Valvojat: Jatta1001, Borrelioosiyhdistys, Bb
BB/VERENLUOVUTUS
Viimeksi muokannut Bb, La Maalis 07, 2009 14:33. Yhteensä muokattu 1 kertaa.
Lähettäjä: Soijuv Lähetetty: 14.2.2006 11:04
Slovakiassa borreliavasta-aineita löydettiin "terveiltä" (mahdollisesti oireettomilta/ lieväoireisilta) henkilöiltä. Borreliavasta-aineet olivat koholla myös useilla verenluovuttajilla.
http://www.ncbi.nlm.nih.gov/entrez/quer ... med_docsum
Bratisl Lek Listy. 2005;106(8-9):270-3.
Reported incidence of Lyme disease in Slovakia and antibodies to B. burgdorferi antigens detected in healthy population.
Bazovska S, Machacova E, Spalekova M, Kontrosova S.
Institute of Epidemiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia. sylvia.bazovska@fmed.uniba.sk
The reported incidence of Lyme disease in Slovakia is indicative of the cyclic character of its appearance, which in the last 10 years rated 12.7/100,000 of the population with typically summer seasonality, prevalence (+20 %) in women, and relative high incidences in the 5-14 and 45-64 age groups. Early forms of the disease were manifested in 70 % of all reported cases. Geographically, the spread of the disease shows major differences in the number of cases reported in the individual districts. Antibodies persist long after the original attack, and there is a high incidence of antibodies in the healthy population in endemic areas.
The presence of antibodies to B. burgdorferi antigens was proven in the serum of 250 blood donors by 3 different screening tests in 4.4-15.6 % of all persons, signifying different sensitivity as well as specificity levels. Subsequent immunoblot examination confirmed the presence of specific antibodies in 12.8 % of all persons, implying high exposure of the population in Slovakia to this infection, although it obviously proceeds in inapparent forms in the majority of cases (Tab. 2, Fig. 4, Ref. 14).
PMID: 16457044 [PubMed - in process]
Slovakiassa borreliavasta-aineita löydettiin "terveiltä" (mahdollisesti oireettomilta/ lieväoireisilta) henkilöiltä. Borreliavasta-aineet olivat koholla myös useilla verenluovuttajilla.
http://www.ncbi.nlm.nih.gov/entrez/quer ... med_docsum
Bratisl Lek Listy. 2005;106(8-9):270-3.
Reported incidence of Lyme disease in Slovakia and antibodies to B. burgdorferi antigens detected in healthy population.
Bazovska S, Machacova E, Spalekova M, Kontrosova S.
Institute of Epidemiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia. sylvia.bazovska@fmed.uniba.sk
The reported incidence of Lyme disease in Slovakia is indicative of the cyclic character of its appearance, which in the last 10 years rated 12.7/100,000 of the population with typically summer seasonality, prevalence (+20 %) in women, and relative high incidences in the 5-14 and 45-64 age groups. Early forms of the disease were manifested in 70 % of all reported cases. Geographically, the spread of the disease shows major differences in the number of cases reported in the individual districts. Antibodies persist long after the original attack, and there is a high incidence of antibodies in the healthy population in endemic areas.
The presence of antibodies to B. burgdorferi antigens was proven in the serum of 250 blood donors by 3 different screening tests in 4.4-15.6 % of all persons, signifying different sensitivity as well as specificity levels. Subsequent immunoblot examination confirmed the presence of specific antibodies in 12.8 % of all persons, implying high exposure of the population in Slovakia to this infection, although it obviously proceeds in inapparent forms in the majority of cases (Tab. 2, Fig. 4, Ref. 14).
PMID: 16457044 [PubMed - in process]