Lähettäjä: Soijuv Lähetetty: 25.12.2005 12:45
1. Verensiirron välityksellä saadusta borrelioosista ei ole tieteellistä näyttöä. Punkkien välityksellä leviää kuitenkin muitakin taudinaiheuttajia joista erityisesti babesioosin leviäminen verivalmisteiden kautta on selkeä uhka. Toisen tutkimuksen mukaan borrelia bakteereita löytyi punasoluista 6 viikkoa jääkaapissa säilyttämisen jälkeenkin:
Curr Opin Hematol. 2003 Nov;10(6):405-11.
Risk and prevention of transfusion-transmitted babesiosis and other tick-borne diseases.
Cable RG, Leiby DA.
American Red Cross, Connecticut Blood Services, Farmington, and University of Connecticut Health Center, Farmington, Connecticut 06032, USA. cabler@usa.redcross.org
PURPOSE OF REVIEW: Tick-borne diseases have increasingly been recognized in the United States as public health problems.
The importance of tick-borne diseases has been accelerated by increases in animal populations, as well as increased human recreation in wooded environments that are conducive to tick bites.
Babesiosis, usually caused by the intraerythrocytic parasite, Babesia microti and transmitted by the same tick as Lyme disease, has important transfusion implications.
Although Lyme disease has not been reported from blood transfusion, newly identified tick-borne diseases such as ehrlichiosis raise additional questions about the role of the tick in transfusion-transmitted diseases.
RECENT FINDINGS: The risk of transfusion-transmitted babesiosis is higher than usually appreciated and in endemic areas represents a major threat to the blood supply.
Furthermore, the geographic range of B. microti is expanding, other Babesia spp. have been implicated in transfusion transmission in the western United States, and the movement of blood donors and donated blood components may result in the appearance of transfusion babesiosis in areas less familiar with these parasites.
Consequently, a higher degree of clinical suspicion will allow early recognition and treatment of this important transfusion complication.
SUMMARY: In endemic areas transfusion-transmitted babesiosis is more prevalent than usually believed. The extension of the geographic range of various Babesia spp. and the movement of donors and blood products around the United States has resulted in the risk extending to non-endemic areas.
Clinicians should maintain a high degree of clinical suspicion for transfusion-transmitted babesiosis.
PMID: 14564169 [PubMed - in process]
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2.
?Viable spirochetes were recovered from RBCs inoculated with 10(6) organisms per mL, after refrigeration for as long as 6 weeks.
It is concluded that B. burgdorferi may survive storage under blood
banking conditions and that transfusion-related Lyme disease is theoretically possible.?
Survival of Borrelia burgdorferi in human blood stored under blood banking conditions.
Nadelman RB; Sherer C; Mack L; Pavia CS; Wormser GP Transfusion, 30(4):298-301. 1990.
BB/BABESIA VERIVALMISTEISSA
Valvojat: Jatta1001, Borrelioosiyhdistys, Bb
BB/BABESIA VERIVALMISTEISSA
Viimeksi muokannut Bb, La Maalis 07, 2009 15:02. Yhteensä muokattu 1 kertaa.
Lähettäjä: Soijuv Lähetetty: 10.2.2006 9:02
Vastasyntynyt lapsi sai babesioosin verensiirrosta! Tutkimuksessa esitetään sen lisäksi muitakin kirjallisuudessa esitettyjä tapauksia babesioosin tarttumisesta; 6 verensiirrosta, 2 synnynnäistä ja 2 punkkien välityksellä saatua tapausta.
Neonatal Babesiosis: Case Report and Review of the Literature.
Pediatric Infectious Disease Journal. 25(2):169-173, February 2006.
Fox, LeAnne M. MD, MPH *+; Wingerter, Sarah MD *; Ahmed, Asim MD *; Arnold, Alana PharmD ++; Chou, Joseph MD, PhD [S]; Rhein, Lawrence MD [S]; Levy, Ofer MD, PhD *
Abstract:
A case of transfusion-associated neonatal babesiosis is presented. Jaundice, hepatosplenomegaly, anemia and conjugated hyperbilirubinemia developed in this preterm infant. The diagnosis was eventually made by blood smear, serology and polymerase chain reaction. The patient was treated with clindamycin and quinine and made a favorable recovery. Of neonatal babesiosis reported in the literature, 9 other cases are reviewed, including 6 that were transfusion-associated, 2 congenital and 2 tick transmitted.
(C) 2006 Lippincott Williams & Wilkins, Inc.
http://www.pidj.org/pt/re/pidj/abstract ... 45!9001!-1
Vastasyntynyt lapsi sai babesioosin verensiirrosta! Tutkimuksessa esitetään sen lisäksi muitakin kirjallisuudessa esitettyjä tapauksia babesioosin tarttumisesta; 6 verensiirrosta, 2 synnynnäistä ja 2 punkkien välityksellä saatua tapausta.
Neonatal Babesiosis: Case Report and Review of the Literature.
Pediatric Infectious Disease Journal. 25(2):169-173, February 2006.
Fox, LeAnne M. MD, MPH *+; Wingerter, Sarah MD *; Ahmed, Asim MD *; Arnold, Alana PharmD ++; Chou, Joseph MD, PhD [S]; Rhein, Lawrence MD [S]; Levy, Ofer MD, PhD *
Abstract:
A case of transfusion-associated neonatal babesiosis is presented. Jaundice, hepatosplenomegaly, anemia and conjugated hyperbilirubinemia developed in this preterm infant. The diagnosis was eventually made by blood smear, serology and polymerase chain reaction. The patient was treated with clindamycin and quinine and made a favorable recovery. Of neonatal babesiosis reported in the literature, 9 other cases are reviewed, including 6 that were transfusion-associated, 2 congenital and 2 tick transmitted.
(C) 2006 Lippincott Williams & Wilkins, Inc.
http://www.pidj.org/pt/re/pidj/abstract ... 45!9001!-1