MS-TAUTI/BORRELIOOSI

[Bb]

Lähettäjä: Soijuv Lähetetty: 8.2.2005 13:10

Useilla borrelioosia sairastavilla on lisäksi MS-diagnoosi tai epäily MS-taudista. Seuraavssa yhdenlainen näkemys borrelioosin ja MS-taudin yhtenevyyksistä ja eroista (v. 2002). Artikkelin mukaan krooninen neuroborrelioosi saattaa aiheuttaa MS-taudin kaltaisia oireita, vaikka ne artikkelin mukaan ovatkin joissakin kohdin toisistaan poikkeavia sairauksia:


Multiple sclerosis and Lyme borreliosis

Erich Schmutzhard Department of Neurology, University Hospital, Innsbruck, Austria
Koko artikkeli:
http://www.springer.at/periodicals/full ... 13_539.pdf


Summary.

In a deductive approach the two disease entities of multiple sclerosis and chronic progressive neuroborreliosis are discussed. Various clinical features, seroepidemiology, neuroimaging, CSF findings, CSF serology, specific proteins within the CSF and antibodies against neuronal structures as well as the most recent findings of different dendritic cells within the CSF are discussed as a means of differentiating these two disease entities.

Conclusion

From this approach of deductive argumentation it is without doubt that acute neuroborreliosis is a clearly distinct disease entity. Similarly without doubt is the fact that any form of chronic neuroborreliosis, e. g. progressive borrelial encephalomyelitis, may present as an MS-like disease; however, there are many ways to clearly differentiate multiple sclerosis from any form of chronic neuroborreliosis.

It is not the task of this deductive outline to discuss either the treatment protocols for the various forms of multiple sclerosis or the distinct treatment protocol for neuroborreliosis (the reader is referred to the published practice guidelines for the treatment of Lyme disease by Wormser et al. [52] and Steere et al. [45]).

Since both treatment options and prognosis are different in these two disease entities (multiple sclerosis and chronic neuroborreliosis) it is necessary to distinguish them as early as possible and with maximum possible certainty, keeping in mind the treatment options and their prognostic aspects.