BORRELIABAKTEERIN LEVIÄMINEN

[Bb]

Lähettäjä: Soijuv Lähetetty: 15.6.2004 9:49

Hei, tässä on jonkin verran tietoa borrelioosin leviämisestä. Bb-bakteeria on löydetty siemennesteestä, emättimen limakalvoilta jne. Kirjoitan asiasta myöhemmin ja laajemmin myöhemmin myös sivuillemme.


.... "Of the more than 5,000 children I've treated, 240 have been born with the disease," says Dr. Jones, who specializes in Pediatric and Adolescent Medicine. "Twelve children who've been breast-fed have subsequently developed Lyme. Bb can be transmitted transplacentally, even with in vitro fertilization; I've seen eight children infected in this way. People from Asia who come to me with the classic Lyme rash have been infected by fleas and gnats."

Gregory Bach, D.O., presented a study on transmission via semen at the American Psychiatric Association meeting in November 2000. He confirmed Bb DNA in semen using the PCR test (Polymerase Chain Reaction). Dr. Bach calls Bb "a brother" to the syphilis spirochete because of their genetic similarities. For that reason, when he treats a Lyme patient in a relationship, he often treats the spouse; otherwise, he says, they can just pass the Bb back and forth, reinfecting each other. Dr. Tang adds other avenues of infection:

"Transmission may also occur via blood transfusion and through the bite of mosquitoes or other insects." Dr. Cowden contends that unpasteurized goat or cow milk can infect a person with Bb.

http://www.centurytel.net/tjs11/bug/l13.htm

This is an abstract presented by Dr. Bach at the International Scientific Conference on Lyme Disease, April, 2001.

RECOVERY OF LYME SPIROCHETES BY PCR IN SEMEN SAMPLES OF PREVIOUSLY DIAGNOSED LYME DISEASE PATIENTS

Dr. Gregory Bach, Do.O., P.C. 2415 North Broad Street, Colmar, PA 18915

OBJECTIVE

Lyme disease, being a spirochete with pathology similar to syphilis, is often found difficult to treat due to the spirochete invading sanctuary sites and displaying pleomorphic characteristics such as a cyst (L-form).

Because a significant portion of sexually active couples present to my office with Lyme disease, with only one partner having a history of tick exposure, the question of possible secondary (sexual)vector of transmission for the spirochete warrants inquiry. Additionally, sexually active couples seem to have a marked propensity for antibiotic failure raising the question of sexually active couples re-infecting themselves through intimate contact.

METHODS: Lyme spirochetes/DNA have been recovered from stored animal semen. Recovery of spirochete DNA from nursing mother's breast milk and umbilical cord blood by PCR (confirmed by culture/microscopy), have been found in samples provided to my office.

RESULTS: Suprisingly, initial laboratory testing of semen samples provided by male Lyme patients (positive by western blot/PCR in blood) and the male sexual partner of a Lyme infected female patient were positive approximately 40% of the time.

PCR recovery of Lyme DNA nucleotide sequences with microscopic confirmation of semen samples yielded positive results in 14/32 Lyme patients (13 male semen samples and 1 vaginal pap). ALL positive semen/vaginal samples in patients with known sexual partners resulted in positive Lyme titers/PCR in their sexual partners. 3/4 positive semen patients had no or unknown sexual partners to be tested. These preliminary findings warrant further study.

Current a statistical design study to evaluate the possibility of sexual transition of the spirochete is being undertaken. Our laboratory studies confirm the existence of Lyme spirochetes in semen/vaginal secretions. Whether or not further clinical studies with a larger statistical group will support the hypothesis of sexual transmission remains to be seen.

A retrospective clinical study is also underway. We are reviewing the medical records, collecting semen samples of patients who were previously diagnosed with current and previously treated Lyme disease are being asked to provide semen, pap and blood samples for extensive laboratory testing.

CONCLUSION: With the initially impressive data, we feel the subsequent statistical study on the sexual transmission of the Lyme spirochete will illuminate a much broader spectrum of public health concerns associated with the disease than the originally accepted tick borne vector.

EVIDENCE FOR TRANSMISSION OF Bb THROUGH INFECTED BODY FLUIDS

FROM ANGILOGY: THE JOURNAL OF VASCULAR DISEASES...
JANUARY 1994. R GASSER, MD,PhD GRAZ, AUSTRIA AND EIGHT OTHER DOCTORS...

"A MOST UNUSUAL CASE OF A WHOLE FAMILY SUFFERING FROM LATE LYME BORRELIOSIS FOR OVER 20 YEARS"
".............HUSBAND HAD NO MEMORY OF A PRIMARY INFECTION WITH CLASSICAL
STAGE ONE SYMPTOMS BUT REMEMBERS RECURRENT EPISODES OF FLU LIKE SYMPTOMS A YEAR AFTER THE INFECTION OF HIS WIFE. THESE EPISODES WERE SOON FOLLOWED BY STAGE TWO AND THREE SYMPTOMS. .......

A SON WAS BORN IN 1969 WITH SEVERAL MINOR ABNORMALITIES....HUGE SACRAL HEMANGIOMA, GLUTEAL ATROPHY, AND OTHERS......GENERALLY WEAK, RECURRENT EPISODES OF FEVER THROUGHOUT HIS LIFE....MINOR MENTAL ABNORMALITIES LIKE IRRITABILITY AND DEPRESSION.....

DIAGNOSIS WAS CONFIRMED IN ALL THREE BY IMMUNOBLOTTING IN OUR SPECIFIC
CLINIC FOR Bb ASSOCIATED DISORDERS.......

FROM THESE CASES TWO IMPORTANT QUESTIONS ARISE:
1. IS THERE A SEXUAL TRANSMISSION...OR OF MERE COINCIDENCE IN AN ENDEMIC
AREA?
2. IS THERE A CONGENITAL LYME DISEASE COMPARIBLE TO CONGENITAL SYPHILIS?

.THE LATTER QUESTION CERTAINLY MERITS FURTHER INVESTIGATION...
.MUCH LARGER CONTROLLED STUDIES ARE NEEDED....

ALTERNATIVELY THERE IS GROWING EXPERIMENTAL EVIDENCE FOR TRANSMISSION OF Bb THROUGH INFECTED BODY FLUIDS. THUS IT HAS BEEN SHOWN THAT Bb CAN BE TRANSMITTED BW CLOSELY HOUSED RESEARCH ANIMALS WITHOUT THE PRESENCE OF INSECTS... (BURGESS EC. EXPERIMENTAL INNOCULATION OF PEROMYSCUSS SPP WITH Bb . AMER JOUR TROP HYG 35; 355-359, 1986.)

THIS LAB EVIDENCE STRONGLY ARGUES IN FAVOR OF TRANSMISSION THROUGH INFECTED BODY FLUIDS. FURTHERMORE MORE THAN 30% OF THE PATIENTS DO NOT REMEMBER A TICK BITE STILL TICK BITES CAN OCCUR WITHOUT THE PT'S BEING AWARE OF THE TICK BITE. A STRONG CORRELATION BETWEEN ANTITICK SALIVA ANTIBODY WAS RECENTLY REPORTED...THUS THERE IS NO DOUBT THAT TICKS ARE THE MOST COMMON TRANSMITTERS OF THE MICROORGANSIM......."