LISÄINFEKTIOISTA
Valvojat: Jatta1001, Borrelioosiyhdistys, Bb
LISÄINFEKTIOISTA
Lähettäjä: Soijuv Lähetetty: 26.1.2006 9:16
Amerikkalaisen tutkimuksen mukaan bartonellaa tavataan yhä useammin ihmisillä ja eläimillä. Bartonellaa sairastavien koirien oireita: aivo-aivokalvontulehdus, hemolyyttinen anemia, sydämen sisäkalvontulehdus, imukudos kasvaimia, trombosytopenia, neitrofilia, moniniveltulehdus.
Am J Vet Res. 2005 Dec;66(12):2060-4.
Clinicopathologic findings in dogs seroreactive to Bartonella henselae antigens.
Goodman RA, Breitschwerdt EB.
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA.
OBJECTIVE: To assess the potential clinical relevance of seroreactivity to Bartonella henselae antigens in dogs. ANIMALS: 40 dogs seroreactive to B henselae and 45 dogs that did not seroreact to B henselae. PROCEDURE: A case-control study was conducted. Clinical and clinicopathologic findings were extracted from medical records of each dog.
RESULTS: Statistical differences were not detected between dogs seroreactive or nonseroreactive to B henselae when analyzed on the basis of disease category or results of hematologic, biochemical, urine, or cytologic analysis. However, seroreactivity to B henselae antigens was detected in 2 of 4 dogs with a clinical diagnosis of granulomatous meningoencephalitis, 3 of 4 dogs with immune-mediated hemolytic anemia, 3 of 4 dogs with infective endocarditis, 2 of 3 dogs with lymphoid neoplasia, and 5 of 10 dogs with polyarthritis. Additionally, seroreactivity to B henselae antigens was detected in 18 of 34 thrombocytopenic dogs and 14 of 27 dogs with neutrophilia.
CONCLUSIONS AND CLINICAL RELEVANCE: Significant associations were not detected between seroreactivity to B henselae and various diseases. Prospective epidemiologic studies investigating specific diseases, such as meningoencephalitis or polyarthritis, and specific hematologic abnormalities, such as immunemediated hemolytic anemia or thrombocytopenia, should be conducted to further define the potential clinical relevance of antibodies against B henselae in dogs.
IMPACT FOR HUMAN MEDICINE: Bartonella organisms are increasingly reported as pathogens that induce chronic infections in humans and dogs. Dogs may serve as natural candidates for future study of the disease in humans.
PMID: 16379647 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/entrez/quer ... med_docsum
Amerikkalaisen tutkimuksen mukaan bartonellaa tavataan yhä useammin ihmisillä ja eläimillä. Bartonellaa sairastavien koirien oireita: aivo-aivokalvontulehdus, hemolyyttinen anemia, sydämen sisäkalvontulehdus, imukudos kasvaimia, trombosytopenia, neitrofilia, moniniveltulehdus.
Am J Vet Res. 2005 Dec;66(12):2060-4.
Clinicopathologic findings in dogs seroreactive to Bartonella henselae antigens.
Goodman RA, Breitschwerdt EB.
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA.
OBJECTIVE: To assess the potential clinical relevance of seroreactivity to Bartonella henselae antigens in dogs. ANIMALS: 40 dogs seroreactive to B henselae and 45 dogs that did not seroreact to B henselae. PROCEDURE: A case-control study was conducted. Clinical and clinicopathologic findings were extracted from medical records of each dog.
RESULTS: Statistical differences were not detected between dogs seroreactive or nonseroreactive to B henselae when analyzed on the basis of disease category or results of hematologic, biochemical, urine, or cytologic analysis. However, seroreactivity to B henselae antigens was detected in 2 of 4 dogs with a clinical diagnosis of granulomatous meningoencephalitis, 3 of 4 dogs with immune-mediated hemolytic anemia, 3 of 4 dogs with infective endocarditis, 2 of 3 dogs with lymphoid neoplasia, and 5 of 10 dogs with polyarthritis. Additionally, seroreactivity to B henselae antigens was detected in 18 of 34 thrombocytopenic dogs and 14 of 27 dogs with neutrophilia.
CONCLUSIONS AND CLINICAL RELEVANCE: Significant associations were not detected between seroreactivity to B henselae and various diseases. Prospective epidemiologic studies investigating specific diseases, such as meningoencephalitis or polyarthritis, and specific hematologic abnormalities, such as immunemediated hemolytic anemia or thrombocytopenia, should be conducted to further define the potential clinical relevance of antibodies against B henselae in dogs.
IMPACT FOR HUMAN MEDICINE: Bartonella organisms are increasingly reported as pathogens that induce chronic infections in humans and dogs. Dogs may serve as natural candidates for future study of the disease in humans.
PMID: 16379647 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/entrez/quer ... med_docsum
Viimeksi muokannut Bb, La Maalis 07, 2009 14:15. Yhteensä muokattu 2 kertaa.
Lähettäjä: Soijuv Lähetetty: 26.1.2006 9:26
Bartonella saattaa aiheutta ihmisille silmien näköhermo- verkkokalvontulehdusta ja äkillistä sokeutta. Pitkän aikavälin ennuste on hyvä, mutta hoito on aloitettava välittömästi (iv antibiootti + steroidit).
J Fr Ophtalmol. 2005 Nov;28(9):968-75.
Abrupt visual loss in children. Three case studies of ocular bartonellosis.
[Article in French]
Depeyre C, Mancel E, Besson-Leaud L, Goursaud R.
Service d'Ophtalmologie, CHT de Noumea.
PURPOSE: To evaluate the severity and progression of neuroretinitis in children caused by Bartonella. PATIENTS AND METHODS: Retrospective study of three consecutive cases. Patients underwent ophthalmological, medical, and radiological evaluations. Bartonella serology was positive. Intravenous treatment was started immediately with antibiotics and steroids. Patients were re-evaluated after visual acuity recovery. RESULTS: Progression was quickly positive with fosfomycin and fluoroquinolones in all cases.
CONCLUSION: Bartonella induces neuroretinitis even without systemic signs of cat-scratch disease, with sometimes sudden bilateral blindness. Long-term progression is good but urgent medical treatment is necessary.
PMID: 16395224 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/entrez/quer ... med_docsum
Bartonella saattaa aiheutta ihmisille silmien näköhermo- verkkokalvontulehdusta ja äkillistä sokeutta. Pitkän aikavälin ennuste on hyvä, mutta hoito on aloitettava välittömästi (iv antibiootti + steroidit).
J Fr Ophtalmol. 2005 Nov;28(9):968-75.
Abrupt visual loss in children. Three case studies of ocular bartonellosis.
[Article in French]
Depeyre C, Mancel E, Besson-Leaud L, Goursaud R.
Service d'Ophtalmologie, CHT de Noumea.
PURPOSE: To evaluate the severity and progression of neuroretinitis in children caused by Bartonella. PATIENTS AND METHODS: Retrospective study of three consecutive cases. Patients underwent ophthalmological, medical, and radiological evaluations. Bartonella serology was positive. Intravenous treatment was started immediately with antibiotics and steroids. Patients were re-evaluated after visual acuity recovery. RESULTS: Progression was quickly positive with fosfomycin and fluoroquinolones in all cases.
CONCLUSION: Bartonella induces neuroretinitis even without systemic signs of cat-scratch disease, with sometimes sudden bilateral blindness. Long-term progression is good but urgent medical treatment is necessary.
PMID: 16395224 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/entrez/quer ... med_docsum
Viimeksi muokannut Bb, La Maalis 07, 2009 14:16. Yhteensä muokattu 1 kertaa.
Lähettäjä: Soijuv Lähetetty: 28.1.2006 9:51
Bartonellaa löydetään usein henkilöiltä joiden immuunijärjestelmä on heikentynyt, mm. useilta ruotsalaisilta huumeenkäyttäjltä:
Ann N Y Acad Sci. 2003 Jun;990:409-13.
Bartonella spp. antibodies in forensic samples from Swedish heroin addicts.
McGill S, Hjelm E, Rajs J, Lindquist O, Friman G.
Infectious Diseases, Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden.
A high frequency of Bartonella elizabethae seropositivity (39%) was recorded among intravenous heroin addicts in Stockholm, Sweden, who died from a lethal injection. Some of the B. elizabethae-seropositive individuals also had antibodies to B. henselae Houston-1, B. grahamii, and B. quintana, but none had antibodies to B. henselae Marseille or B. vinsonii subsp. vinsonii. Hepatitis was a frequent finding but no case had peliosis hepatitis. There was no case of endocarditis, but in three persons active subacute-to-chronic myocarditis was found; two of these cases were Bartonella-positive and HIV-negative.
PMID: 12860665 [PubMed - indexed for MEDLINE]
1: APMIS. 2003 Apr;111(4):507-13. Related Articles, Links
A study on forensic samples of Bartonella spp antibodies in Swedish
intravenous heroin addicts.
McGill S, Rajs J, Hjelm E, Lindquist O, Friman G.
Infectious Diseases, Department of Surgical Sciences, Uppsala University
Hospital, Uppsala, Sweden.
Infection with Bartonella, an emerging bacterial pathogen which often affects immunodeficient patients, has been reported in Sweden over the past few years, with a high seroprevalence of B. elizabethae. A high prevalence of antibodies against B. elizabethae has also been found in urban intravenous drug users in the USA. Using immunofluorescence, we retrospectively examined serum samples taken at autopsy from 59 Swedish intravenous drug addicts from the Stockholm area for evidence of antibodies against 6 pathogenic strains of Bartonella.
The 59 addicts died following heroin injection during the years 1987-1992 and include 24 individuals (41%) who were additionally HIV-positive. An overall seropositivity rate for Bartonella spp. of 39% (23/59) was found with the following antigenic reactivities: B. elizabethae, 39% (23/59); B. grahamii, 3% (2/59); B. henselae (Houston-1), 14% (8/59); and B. quintana, 3% (2/59). There were no positive reactions for B. henselae (Marseille) or B. vinsonii subsp. vinsonii. The Bartonella-seropositive cases included 11/23 (48%) individuals who were HIV-positive. Subacute to chronic myocarditis was seen in 2/11 microscopically investigated Bartonella-seropositive cases that were HIV-negative and in 1/14 seronegative cases. No cases of endocarditis or other common manifestations of Bartonella infection were found. An overall Bartonella seropositivity of 21% (9/44) was observed in control forensic autopsy samples.
PMID: 12780526 [PubMed - indexed for MEDLINE]
Bartonellaa löydetään usein henkilöiltä joiden immuunijärjestelmä on heikentynyt, mm. useilta ruotsalaisilta huumeenkäyttäjltä:
Ann N Y Acad Sci. 2003 Jun;990:409-13.
Bartonella spp. antibodies in forensic samples from Swedish heroin addicts.
McGill S, Hjelm E, Rajs J, Lindquist O, Friman G.
Infectious Diseases, Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden.
A high frequency of Bartonella elizabethae seropositivity (39%) was recorded among intravenous heroin addicts in Stockholm, Sweden, who died from a lethal injection. Some of the B. elizabethae-seropositive individuals also had antibodies to B. henselae Houston-1, B. grahamii, and B. quintana, but none had antibodies to B. henselae Marseille or B. vinsonii subsp. vinsonii. Hepatitis was a frequent finding but no case had peliosis hepatitis. There was no case of endocarditis, but in three persons active subacute-to-chronic myocarditis was found; two of these cases were Bartonella-positive and HIV-negative.
PMID: 12860665 [PubMed - indexed for MEDLINE]
1: APMIS. 2003 Apr;111(4):507-13. Related Articles, Links
A study on forensic samples of Bartonella spp antibodies in Swedish
intravenous heroin addicts.
McGill S, Rajs J, Hjelm E, Lindquist O, Friman G.
Infectious Diseases, Department of Surgical Sciences, Uppsala University
Hospital, Uppsala, Sweden.
Infection with Bartonella, an emerging bacterial pathogen which often affects immunodeficient patients, has been reported in Sweden over the past few years, with a high seroprevalence of B. elizabethae. A high prevalence of antibodies against B. elizabethae has also been found in urban intravenous drug users in the USA. Using immunofluorescence, we retrospectively examined serum samples taken at autopsy from 59 Swedish intravenous drug addicts from the Stockholm area for evidence of antibodies against 6 pathogenic strains of Bartonella.
The 59 addicts died following heroin injection during the years 1987-1992 and include 24 individuals (41%) who were additionally HIV-positive. An overall seropositivity rate for Bartonella spp. of 39% (23/59) was found with the following antigenic reactivities: B. elizabethae, 39% (23/59); B. grahamii, 3% (2/59); B. henselae (Houston-1), 14% (8/59); and B. quintana, 3% (2/59). There were no positive reactions for B. henselae (Marseille) or B. vinsonii subsp. vinsonii. The Bartonella-seropositive cases included 11/23 (48%) individuals who were HIV-positive. Subacute to chronic myocarditis was seen in 2/11 microscopically investigated Bartonella-seropositive cases that were HIV-negative and in 1/14 seronegative cases. No cases of endocarditis or other common manifestations of Bartonella infection were found. An overall Bartonella seropositivity of 21% (9/44) was observed in control forensic autopsy samples.
PMID: 12780526 [PubMed - indexed for MEDLINE]
Viimeksi muokannut Bb, La Maalis 07, 2009 14:18. Yhteensä muokattu 2 kertaa.
Lähettäjä: Soijuv Lähetetty: 22.2.2006 16:39
Artikkelin mukaan borrelioosi kroonistuu nimenomaan sellaisilla henkilöillä, jotka saavat punkinpureman mukana useampia taudinaiheuttajia elimistöönsä. Useimmiten se on mykoplasma.
Kroonisessa borrelioosissa esiintyy yksi tai useampia seuraavista taudinaiheuttajista: esim. spirokeettoja, mykoplasmoja, klamydiaa, bartonellaa, babesioosia, ehrlichioosia, riketsioita jne.
Tämä saattaa selittää sen miksi toisilla borrelioosi paranee parin viikon antibiooteilla ja toisilla ei millään standardihoidoilla. Tätä näkökulmaa taudin hoidossa ei huomioida tällä hetkellä laisinkaan.
Below is an excerpt from an article written by Sean & Leslee Dudlee who are the founders of the Micoplasma Registry (a Yahoo Group).
* * * * * * * * * * * * * * * * * * * * * * * * *
Systemic Mycoplasma Infections are found in patients with:
Gulf War Syndrome, Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Fibromyalgia, Lyme Disease, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Scleroderma, Sjogren's Syndrome, Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Cystic Fibrosis, Asthma, Respiratory Distress Syndrome, Pneumonia, Bronchitis, Inflammatory Bowel Disease, Sarcoidosis, Wegener's Disease, Kikuchi's Disease, Leukemia, Alzheimer's Disease, Autism, Infertility, Stevens- Johnson Syndrome, and Acquired Immune Deficiency Syndrome, Hypercoagulation, Heart Disease, Stroke and Cancer.
LYME DISEASE
"CHRONIC LYME DISEASE" or "NEW LYME DISEASE"
"MONTANA LYME DISEASE"
If bitten by ticks or fleas carrying Borrelia burgdorferi you can develop traditional Lyme Disease, which is self-limiting and carried by a deer tick. Our experience with patients suggests that if the tick or flea also carries co-infections, such as Babesiosis or especially Mycoplasmas, you may develop "Chronic Lyme Disease" also known as "New Lyme Disease" as well as Chronic Fatigue Syndrome, Fibromyalgia and Autoimmune Diseases.
"MONTANA LYME DISEASE" symptoms are similar to Lyme Disease. However, it is caused by a Lyme disease-like agent that has adapted to the
Rocky Mountain wood ticks found in Montana and the Western United States.
LYME DISEASE caused by three types of Spirochete Borrelia bacteria:
1. Borrelia burgdorferi sensu stricto(USA,UK,Europe)
2. Borrelia garinii (UK, Europe)
3. Borrelia afzelii (UK, Europe)
"CHRONIC LYME DISEASE" or "NEW LYME DISEASE"
is a combination of LYME DISEASE and
one or more of the following Co-infections:
Relapsing Fever caused by the spirochetes:
- Borrelia hermsii
- Borrelia turicatae
Mycoplasmas:
- Mycoplasma fermentans
- Mycoplasma pneumoniae
Babesiosis:
- Babesia microti
- Babesia WA
- Chlamydia pneumoniae
Rickettsial Diseases:
- Rocky Mountain Spotted Fever
- Coxiella burnetti (Q-Fever and "Post-Q Fever Fatigue Syndrome")
- Colorado Tick Fever
- Eastern tick-borne Rickettsiosis
- Rickettsialpox
- Tularemia (rabbit fever)
- Ehrlichiosis (caused by Ehrlichia, a rickettsia-like bacteria)
- Anaplasmas (related to the genera Rickettsia and Ehrlichia)
- Hepatitis-C
Bartonellosis:
- Bartonella henselae (cat scratch fever)
- Bartonella quintana (trench fever)
- Viral Meningitis
Artikkelin mukaan borrelioosi kroonistuu nimenomaan sellaisilla henkilöillä, jotka saavat punkinpureman mukana useampia taudinaiheuttajia elimistöönsä. Useimmiten se on mykoplasma.
Kroonisessa borrelioosissa esiintyy yksi tai useampia seuraavista taudinaiheuttajista: esim. spirokeettoja, mykoplasmoja, klamydiaa, bartonellaa, babesioosia, ehrlichioosia, riketsioita jne.
Tämä saattaa selittää sen miksi toisilla borrelioosi paranee parin viikon antibiooteilla ja toisilla ei millään standardihoidoilla. Tätä näkökulmaa taudin hoidossa ei huomioida tällä hetkellä laisinkaan.
Below is an excerpt from an article written by Sean & Leslee Dudlee who are the founders of the Micoplasma Registry (a Yahoo Group).
* * * * * * * * * * * * * * * * * * * * * * * * *
Systemic Mycoplasma Infections are found in patients with:
Gulf War Syndrome, Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Fibromyalgia, Lyme Disease, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Scleroderma, Sjogren's Syndrome, Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Cystic Fibrosis, Asthma, Respiratory Distress Syndrome, Pneumonia, Bronchitis, Inflammatory Bowel Disease, Sarcoidosis, Wegener's Disease, Kikuchi's Disease, Leukemia, Alzheimer's Disease, Autism, Infertility, Stevens- Johnson Syndrome, and Acquired Immune Deficiency Syndrome, Hypercoagulation, Heart Disease, Stroke and Cancer.
LYME DISEASE
"CHRONIC LYME DISEASE" or "NEW LYME DISEASE"
"MONTANA LYME DISEASE"
If bitten by ticks or fleas carrying Borrelia burgdorferi you can develop traditional Lyme Disease, which is self-limiting and carried by a deer tick. Our experience with patients suggests that if the tick or flea also carries co-infections, such as Babesiosis or especially Mycoplasmas, you may develop "Chronic Lyme Disease" also known as "New Lyme Disease" as well as Chronic Fatigue Syndrome, Fibromyalgia and Autoimmune Diseases.
"MONTANA LYME DISEASE" symptoms are similar to Lyme Disease. However, it is caused by a Lyme disease-like agent that has adapted to the
Rocky Mountain wood ticks found in Montana and the Western United States.
LYME DISEASE caused by three types of Spirochete Borrelia bacteria:
1. Borrelia burgdorferi sensu stricto(USA,UK,Europe)
2. Borrelia garinii (UK, Europe)
3. Borrelia afzelii (UK, Europe)
"CHRONIC LYME DISEASE" or "NEW LYME DISEASE"
is a combination of LYME DISEASE and
one or more of the following Co-infections:
Relapsing Fever caused by the spirochetes:
- Borrelia hermsii
- Borrelia turicatae
Mycoplasmas:
- Mycoplasma fermentans
- Mycoplasma pneumoniae
Babesiosis:
- Babesia microti
- Babesia WA
- Chlamydia pneumoniae
Rickettsial Diseases:
- Rocky Mountain Spotted Fever
- Coxiella burnetti (Q-Fever and "Post-Q Fever Fatigue Syndrome")
- Colorado Tick Fever
- Eastern tick-borne Rickettsiosis
- Rickettsialpox
- Tularemia (rabbit fever)
- Ehrlichiosis (caused by Ehrlichia, a rickettsia-like bacteria)
- Anaplasmas (related to the genera Rickettsia and Ehrlichia)
- Hepatitis-C
Bartonellosis:
- Bartonella henselae (cat scratch fever)
- Bartonella quintana (trench fever)
- Viral Meningitis